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典型文献
应用污水流行病学方法调查四川省氟胺酮滥用量
文献摘要:
目的:利用污水流行病学方法分析污水样本中氟胺酮及去甲氟胺酮的浓度,以估算四川省氟胺酮的滥用量.方法:2021年7月至2022年3月期间,每季度采集一次全省170余个污水处理厂工作日和公休日的污水样本,固相萃取后利用三重四极杆液质联用仪测定污水中的氟胺酮和去甲氟胺酮的浓度,并结合污水处理厂进水口流量、服务人口数量及代谢率等参数估算氟胺酮的滥用量.结果:三次监测中氟胺酮的最高浓度分别为31.90 ng/L、14.90 ng/L、8.90 ng/L,氟胺酮的最高滥用量分别为82.68 mg/千人·d、33.17 mg/千人·d、5.99 mg/千人·d,全省工作日氟胺酮滥用量分别为4.05 mg/千人·d、5.23 mg/千人·d、0.71 mg/千人·d,公休日的分别为13.05 mg/千人·d、5.57 mg/千人·d、0.71 mg/千人·d.结论:连续监测期间,全省氟胺酮滥用量呈大幅下降趋势,当污水样品中氟胺酮和去甲氟胺酮的浓度比值大小在1.61~5.32时,为吸食毒品氟胺酮后正常代谢所产生.
文献关键词:
污水流行病学;氟胺酮;滥用量
作者姓名:
杨丽;白登文;杨淑颐;仇文璞;祁观;柴一麟;叶懿;徐布一
作者机构:
国家毒品实验室四川分中心,四川成都 614000;四川大学华西基础医学与法医学院法医毒物分析教研室,四川成都 614000
引用格式:
[1]杨丽;白登文;杨淑颐;仇文璞;祁观;柴一麟;叶懿;徐布一-.应用污水流行病学方法调查四川省氟胺酮滥用量)[J].中国药物滥用防治杂志,2022(10):1362-1369,1391
A类:
滥用量,公休日
B类:
污水流行病学,流行病学方法,水样,去甲氟胺酮,每季度,余个,污水处理厂,工作日,固相萃取,三重四极杆,液质联用仪,进水口,人口数量,代谢率,参数估算,省工,连续监测,吸食毒品
AB值:
0.15691
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