典型文献
Roles of Gut Microbiota in Pathogenesis of Alzheimer's Disease and Therapeutic Effects of Chinese Medicine
文献摘要:
Alzheimer's disease(AD)is the most common neurodegenerative disease characterized by progressive cognitive impairment.The pathogenesis of AD is complex,and its susceptibility and development process are affected by age,genetic and epigenetic factors.Recent studies confirmed that gut microbiota(GM)might contribute to AD through a variety of pathways including hypothalamic pituitary adrenal axis and inflammatory and immune processes.CM formula,herbs,and monomer enjoy unique advantages to treat and prevent AD.Hence,the purpose of this review is to outline the roles of GM and its core metabolites in the pathogenesis of AD.Research progress of CMs regarding the mechanisms of how they regulate GM to improve cognitive impairment of AD is also reviewed.The authors tried to explore new therapeutic strategies to AD based on the regulation of GM using CM.
文献关键词:
中图分类号:
作者姓名:
SUN Ying-xin;JIANG Xi-juan;LU Bin;GAO Qing;CHEN Ye-fei;WU Dan-bin;ZENG Wen-yun;YANG Lin;LI Hu-hu;YU Bin
作者机构:
School of Integrative Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China
文献出处:
引用格式:
[1]SUN Ying-xin;JIANG Xi-juan;LU Bin;GAO Qing;CHEN Ye-fei;WU Dan-bin;ZENG Wen-yun;YANG Lin;LI Hu-hu;YU Bin-.Roles of Gut Microbiota in Pathogenesis of Alzheimer's Disease and Therapeutic Effects of Chinese Medicine)[J].中国结合医学杂志(英文版),2022(11):1048-1056
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AB值:
0.694226
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