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典型文献
Viral Tools for Neural Circuit Tracing
文献摘要:
Neural circuits provide an anatomical basis for functional networks.Therefore,dissecting the structure of neural circuits is essential to understanding how the brain works.Recombinant neurotropic viruses are important tools for neural circuit tracing with many advantages over non-viral tracers:they allow for anterograde,retrograde,and trans-synaptic delivery of tracers in a cell type-specific,circuit-selective manner.In this review,we summarize the recent developments in the viral tools for neural circuit trac-ing,discuss the key principles of using viral tools in neuro-science research,and highlight innovations for developing and optimizing viral tools for neural circuit tracing across diverse animal species,including nonhuman primates.
文献关键词:
作者姓名:
Qing Liu;Yang Wu;Huadong Wang;Fan Jia;Fuqiang Xu
作者机构:
The Brain Cognition and Brain Disease Institute(BCBDI),Shenzhen Key Laboratory of Viral Vectors for Biomedicine,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions,NMPA Key Laboratory for Research and Evaluation of Viral Vector Technology in Cell and Gene Therapy Medicinal Products,Shenzhen Key Laboratory of Quality Control Technology for Virus-Based Therapeutics,Guangdong Provincial Medical Products Administration,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,China;University of Chinese Academy of Sciences,Beijing 100049,China;State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics,Key Laboratory of Magnetic Resonance in Biological Systems,Wuhan Center for Magnetic Resonance,Innovation Academy for Precision Measurement Science and Technology,Chinese Academy of Sciences,Wuhan 430071,China;Center for Excellence in Brain Science and Intelligence Technology,Chinese Academy of Sciences,Shanghai 200031,China
引用格式:
[1]Qing Liu;Yang Wu;Huadong Wang;Fan Jia;Fuqiang Xu-.Viral Tools for Neural Circuit Tracing)[J].神经科学通报(英文版),2022(12):1508-1518
A类:
anterograde
B类:
Viral,Tools,Neural,Circuit,Tracing,circuits,provide,anatomical,basis,functional,networks,Therefore,dissecting,structure,neural,essential,understanding,how,brain,Recombinant,neurotropic,viruses,are,important,tools,tracing,many,advantages,over,viral,tracers,they,allow,retrograde,trans,synaptic,delivery,cell,type,specific,selective,manner,In,this,review,we,summarize,recent,developments,discuss,key,principles,using,science,research,highlight,innovations,developing,optimizing,across,diverse,animal,species,including,nonhuman,primates
AB值:
0.643201
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