典型文献
Acceptorless dehydrogenative amination of alkenes for the synthesis of N-heterocycles
文献摘要：
Catalytic amination of alkenes is one of the most attractive reactions for the construction of complex heterocycles with nitrogen centers.Herein,we present that synergistic photoredox and cobaloxime catalysis allows for highly efficient and mild dehy-drogenative reactions between various NH nucleophiles and di-,tri-,and tetrasubstituted alkenes in the absence of external oxidants,thus enabling access to an array of N-heterocycles.Notably,both Z-and E-alkene-containing N-heterocycles are accessible.Mechanistic studies indicated that the Z-cinnamyl derivatives could be generated by photocatalytic E to Z alkene isomerization through an energy transfer process.Moreover,we find that sluggish energy transfer could inhibit the E to Z alkene isomerization process,thus offering the cinnamyl derivatives with E-selectivity.Our results highlight the benefits of the reactions using dual photoredox and cobaloxime catalysis to lead to diverse N-heterocycles.
文献关键词：
中图分类号：
作者姓名：
Jia-Lin Tu;Wan Tang;Shi-Hui He;Ma Su;Feng Liu
作者机构：
Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Medicinal Chemistry,College of Pharmaceutical Sciences,Soochow University,Suzhou 215123,China;Key Laboratory of Organofluorine Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China
文献出处：
引用格式：
[1]Jia-Lin Tu;Wan Tang;Shi-Hui He;Ma Su;Feng Liu-.Acceptorless dehydrogenative amination of alkenes for the synthesis of N-heterocycles)[J].中国科学:化学（英文版）,2022(07):1330-1337
A类：
Acceptorless,cobaloxime,drogenative,tetrasubstituted
B类：
dehydrogenative,amination,alkenes,synthesis,heterocycles,Catalytic,one,most,attractive,reactions,construction,complex,nitrogen,centers,Herein,present,that,synergistic,photoredox,catalysis,allows,highly,efficient,mild,between,various,NH,nucleophiles,tri,absence,external,oxidants,thus,enabling,array,Notably,both,containing,are,accessible,Mechanistic,studies,indicated,cinnamyl,derivatives,could,generated,by,photocatalytic,isomerization,through,energy,transfer,process,Moreover,find,sluggish,inhibit,offering,selectivity,Our,results,highlight,benefits,using,dual,lead,diverse
AB值：
0.525592
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