典型文献
Off-the-shelf CAR T cells to treat cancer
文献摘要：
Chimeric antigen receptor(CAR)T cell therapies approved for cancer treatment are manufactured from a patient's own cells(autologous),entailing challenges such as high costs,incon-sistent product quality,and potential treatment failure due to T cell dysfunction.In a study published in Cell Research,Hu et al.generated CAR T cells from healthy donor T cells(allogeneic),and these were successful in a clinical trial for the treatment of T cell malignancies.
文献关键词：
中图分类号：
作者姓名：
Sofia Castelli;Regina M.Young;Carl H.June
作者机构：
Center for Cellular Immunotherapies,University of Pennsylvania Perelman School of Medicine,Philadelphia,PA,USA
文献出处：
引用格式：
[1]Sofia Castelli;Regina M.Young;Carl H.June-.Off-the-shelf CAR T cells to treat cancer)[J].细胞研究（英文版）,2022(12):1036-1037
A类：
entailing,incon
B类：
Off,shelf,CAR,cells,cancer,Chimeric,antigen,receptor,therapies,approved,treatment,are,manufactured,from,patient,own,autologous,challenges,such,as,high,costs,sistent,product,quality,potential,failure,due,dysfunction,In,study,published,Cell,Research,Hu,et,generated,healthy,donor,allogeneic,these,were,successful,clinical,trial,malignancies
AB值：
0.695242
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