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典型文献
Transcriptomic profiling fuels the derivation of stable pig epiblast stem cells
文献摘要:
It is controversial whether pig pluripotent stem cells can be derived and stably maintained in a culture dish.In a recent paper published in Cell Research,Zhi et al.perform a comprehensive transcriptome landscape analysis of pig embryos at all developmental stages from embryonic(E)day 0 to E14 and identify a culture cocktail to stabilize pig pregastrulation epiblast stem cells(pgEpiSCs)in vitro for long-term passaging;the pgEpiSCs can undergo multiple rounds of gene editing and generate cloned animals.
文献关键词:
作者姓名:
Cuiqing Zhong;Ronghui Li;Juan Carlos Izpisua Belmonte
作者机构:
Altos Labs,San Diego,CA,USA;Salk Institute for Biological Studies,La Jolla,CA,USA
引用格式:
[1]Cuiqing Zhong;Ronghui Li;Juan Carlos Izpisua Belmonte-.Transcriptomic profiling fuels the derivation of stable pig epiblast stem cells)[J].细胞研究(英文版),2022(04):329-330
A类:
pregastrulation,pgEpiSCs,passaging
B类:
Transcriptomic,profiling,fuels,derivation,stable,pig,epiblast,stem,cells,It,controversial,whether,pluripotent,can,be,derived,stably,maintained,culture,dish,In,recent,paper,published,Cell,Research,Zhi,perform,comprehensive,transcriptome,landscape,analysis,embryos,all,developmental,stages,from,embryonic,day,E14,identify,cocktail,stabilize,vitro,long,term,undergo,multiple,rounds,editing,generate,cloned,animals
AB值:
0.664441
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