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典型文献
Phenylarsine oxide inhibits the accumulation of lipid droplets in macrophages
文献摘要:
Intracellular accumulation of esterified cholesterol-containing lipid droplets,which leads to the formation of foam cells associated with related inflammatory reactions,is the core pathological event in atherosclerosis[1,2].Cardiovascular and cerebrovascular diseases caused by atherosclerosis remain the leading causes of human death and disability after decades of clinical application of highly effective lipid-lowering treatment[3,4].Clearly,lowering lipids alone or even in combination with some potential anti-inflamma-tion resolution is far from enough to prevent and treat athero-sclerosis-induced vascular disease,demanding new approaches and/or therapeutic targets for anti-atherosclerosis.
文献关键词:
作者姓名:
Yuyu Xie;Jason Huang;Hao Zhang;Feng Hong;Fu-De Huang;Wen-An Wang
作者机构:
Department of Neurology,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200092,China;Department of Neurology,Chongming Hospital Affiliate to Shanghai University of Medicine&Health Science,Shanghai 202150,China;Nuo-beta Pharmaceutical Technology(Shanghai)Co.Ltd.,Shanghai 201210,China;Sino-Danish College,University of Chinese Academy of Sciences,Beijing 100190,China
引用格式:
[1]Yuyu Xie;Jason Huang;Hao Zhang;Feng Hong;Fu-De Huang;Wen-An Wang-.Phenylarsine oxide inhibits the accumulation of lipid droplets in macrophages)[J].生物化学与生物物理学报(英文版),2022(12):1931-1934
A类:
Phenylarsine
B类:
oxide,inhibits,accumulation,droplets,macrophages,Intracellular,esterified,cholesterol,containing,which,leads,formation,foam,cells,associated,related,inflammatory,reactions,core,pathological,atherosclerosis,Cardiovascular,cerebrovascular,diseases,caused,by,remain,leading,causes,human,death,disability,after,decades,clinical,application,highly,effective,lowering,treatment,Clearly,lipids,alone,combination,some,potential,anti,resolution,far,from,enough,prevent,induced,demanding,new,approaches,therapeutic,targets
AB值:
0.628764
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