典型文献
Targeting postprandial glucose control using ultra-rapid insulins:is faster better?
文献摘要：
Type 2 diabetes(T2D)is characterised by defects in both fasting and postprandial glucose(PPG)control.Many Asians including Chinese people with T2D have isolated high PPG at diagnosis with-out concomitant elevation in fasting plasma glucose(FPG).This might be due to differences in genetic architecture,low insulin secretion,and high carbohydrate diet in East Asians.Excursions in PPG contribute significantly to glycemic variability(GV),which is associated with increased risk of cardiovascular-renal-cancer events[1].Asians with T2D are less likely to achieve target hemo-globin A1c(HbA1c)of＜7％using basal insulin alone than non-Asians.In a meta-analysis of randomised controlled trials in patients started on insulin glargine 100 U/mL,40％Asian vs.47％non-Asian patients achieved target HbA1c of＜7％despite achiev-ing optimal FPG[2].In a small study of insulin-naive Chinese patients with T2D initiated on second-generation basal insulin analogues,elevated PPG contributed significantly to suboptimal HbA1c and time-above-range and GV on continuous glucose mon-itoring(CGM),despite optimisation of FPG[3].
文献关键词：
中图分类号：
作者姓名：
Elaine Chow;Juliana C.N.Chan
作者机构：
Department of Medicine and Therapeutics,The Chinese University of Hong Kong,Prince of Wales Hospital,Hong Kong,China;Hong Kong Institute of Diabetes and Obesity,The Chinese University of Hong Kong,Prince of Wales Hospital,Hong Kong,China;Phase 1 Clinical Trial Centre,The Chinese University of Hong Kong,Prince of Wales Hospital,Hong Kong,China;Li Ka Shing Institute of Health Sciences,The Chinese University of Hong Kong,Prince of Wales Hospital,Hong Kong,China
文献出处：
引用格式：
[1]Elaine Chow;Juliana C.N.Chan-.Targeting postprandial glucose control using ultra-rapid insulins:is faster better?)[J].科学通报（英文版）,2022(23):2392-2394
A类：
insulins,Excursions,glargine
B类：
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AB值：
0.564369
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
