典型文献
Engineered Vasculature for Organ-on-a-Chip Systems
文献摘要：
Organ-on-a-chip technology,a promising three-dimensional(3D)dynamic culture method,ensures accu-rate and efficient cell culture and has great potential for replacing animal models in preclinical testing.The circulatory system,the most abundant organ in the human body,plays a crucial role in oxygen exchange and mass transfer,which is the determining factor for the survival of tissues and organs.Thus,it is essential to integrate the circulatory system into an organ-on-a-chip to recreate tissue and organ microenvironments and physiological functions.This review discusses the synergy between the vasculature and the emerging organ-on-a-chip technology,which offers even better possibilities of dupli-cating physiology and disease characteristics.In addition,we review the different steps of a vascularized organ-on-a-chip fabrication process,including structure fabrication and tissue construction using differ-ent biofabrication strategies.Finally,we outline the applicability of this technology in the fascinating and fast-developing field of organ and tumor culture.
文献关键词：
中图分类号：
作者姓名：
Abdellah Aazmi;Hongzhao Zhou;Yuting Li;Mengfei Yu;Xiaobin Xu;Yutong Wu;Liang Ma;Bin Zhang;Huayong Yang
作者机构：
State Key Laboratory of Fluid Power and Mechatronic Systems,Zhejiang University,Hangzhou 310058,China;School of Mechanical Engineering,Zhejiang University,Hangzhou 310058,China;The Affiliated Stomatologic Hospital,School of Medicine,Zhejiang University,Hangzhou 310003,China;School of Materials Science and Engineering,Tongji University,Shanghai 201804,China
文献出处：
引用格式：
[1]Abdellah Aazmi;Hongzhao Zhou;Yuting Li;Mengfei Yu;Xiaobin Xu;Yutong Wu;Liang Ma;Bin Zhang;Huayong Yang-.Engineered Vasculature for Organ-on-a-Chip Systems)[J].工程（英文）,2022(02):131-147
A类：
dupli,biofabrication
B类：
Engineered,Vasculature,Organ,Chip,Systems,chip,technology,promising,three,dimensional,dynamic,culture,method,ensures,accu,efficient,cell,has,great,potential,replacing,animal,models,preclinical,testing,circulatory,system,most,abundant,human,body,plays,crucial,role,oxygen,exchange,mass,transfer,which,determining,survival,tissues,organs,Thus,essential,integrate,into,recreate,microenvironments,physiological,functions,This,review,discusses,synergy,between,vasculature,emerging,offers,even,better,possibilities,cating,physiology,disease,characteristics,In,addition,different,steps,vascularized,process,including,structure,construction,using,strategies,Finally,outline,applicability,this,fascinating,fast,developing,field,tumor
AB值：
0.614103
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