典型文献
A Review of Nano/Micro/Millli Needles Fabrications for Biomedical Engineering
文献摘要：
Needles,as some of the most widely used medical devices,have been effectively applied in human disease preven-tion,diagnosis,treatment,and rehabilitation.Thin 1D needle can easily penetrate cells/organs by generating highly localized stress with their sharp tips to achieve bioliquid sampling,biosensing,drug delivery,surgery,and other such applications.In this review,we provide an overview of multiscale needle fabrication techniques and their biomedical applications.Needles are classified as nanoneedles,microneedles and millineedles based on the needle diameter,and their fabrication techniques are highlighted.Nanoneedles bridge the inside and outside of cells,achieving intracel-lular electrical recording,biochemical sensing,and drug delivery.Microneedles penetrate the stratum corneum layer to detect biomarkers/bioelectricity in interstitial fluid and deliver drugs through the skin into the human circulatory system.Millineedles,including puncture,syringe,acupuncture and suture needles,are presented.Finally,conclusions and future perspectives for next-generation nano/micro/milli needles are discussed.
文献关键词：
中图分类号：
作者姓名：
Bin Liu;Xin Yi;Ying Zheng;Zhishan Yuan;Jingbo Yang;Jian Yang;Xiao Yu;Lelun Jiang;Chengyong Wang
作者机构：
Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instruments,School of Biomedical Engineering,Shenzhen Campus of Sun Yat-sen University,Shenzhen 518107,China;Guangdong Provincial Key Laboratory of Minimally Invasive Surgical
文献出处：
引用格式：
[1]Bin Liu;Xin Yi;Ying Zheng;Zhishan Yuan;Jingbo Yang;Jian Yang;Xiao Yu;Lelun Jiang;Chengyong Wang-.A Review of Nano/Micro/Millli Needles Fabrications for Biomedical Engineering)[J].中国机械工程学报,2022(03):51-79
A类：
Millli,Fabrications,bioliquid,millineedles,Nanoneedles,Microneedles,Millineedles
B类：
Review,Needles,Biomedical,Engineering,some,most,widely,used,devices,have,been,effectively,applied,human,disease,preven,diagnosis,treatment,rehabilitation,Thin,1D,can,easily,penetrate,cells,organs,by,generating,highly,localized,stress,their,sharp,tips,achieve,sampling,biosensing,delivery,surgery,other,such,applications,In,this,review,we,provide,overview,multiscale,fabrication,techniques,biomedical,are,classified,nanoneedles,microneedles,diameter,highlighted,bridge,inside,outside,achieving,intracel,lular,electrical,recording,biochemical,stratum,corneum,layer,detect,biomarkers,bioelectricity,interstitial,fluid,drugs,through,skin,into,circulatory,system,including,syringe,acupuncture,suture,presented,Finally,conclusions,future,perspectives,next,generation,discussed
AB值：
0.611253
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