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典型文献
A scoping review of SARS-CoV-2 and male infertility: Concerns and future prospects
文献摘要:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been detected in the blood, urine, facial/anal swabs, semen, and vaginal discharge; all have been shown to contain SARS-CoV-2 RNA. Recent findings have highlighted the prospect of SARS-CoV-2 invading the genital system in addition to other tissues, which might give rise to reproductive concerns. This investigation sheds light on male reproductive tract vulnerability to invasion by SARS-CoV-2 and provides a foundation for further researches into male fertility. Males are infected with COVID-19 at a higher rate than females. As a result, some data suggest that this viral infection might affect the male reproductive system. The probable causes for male genital tract abnormalities in COVID-19 are: 1) high expression of angiotensin-converting enzyme 2 in the testes; 2) SARS-CoV-2 infection indirectly induces immune response in the testes; 3) SARS-CoV-2 directly damages male genital cells by virus-receptor binding activity; 4) fever in SARS-CoV-2 infected males may cause damages to testicular cells; 5) testosterone level decreased in SAR-CoV-2 infected males; 6) males are more susceptible to COVID-19 than females, which may be due to differences in the physiology of the genital tract. This review seeks to offer some insights into the potential causes of COVID-19 that affect the male reproductive system, as well as future prospect on this issue.
文献关键词:
作者姓名:
Falah Hasan Obayes AL-Khikani;Aalae Salman Ayit
作者机构:
Medical Technique Department,College of Medical Technique,The Islamic University,Babylon,Iraq
引用格式:
[1]Falah Hasan Obayes AL-Khikani;Aalae Salman Ayit-.A scoping review of SARS-CoV-2 and male infertility: Concerns and future prospects)[J].亚太生殖杂志(英文版),2022(02):53-61
A类:
B类:
scoping,review,SARS,CoV,infertility,Concerns,future,prospects,Severe,acute,respiratory,syndrome,coronavirus,has,been,detected,blood,urine,facial,anal,swabs,semen,vaginal,discharge,all,have,shown,contain,Recent,findings,highlighted,invading,genital,system,addition,other,tissues,which,might,give,rise,reproductive,concerns,This,investigation,sheds,tract,vulnerability,invasion,by,provides,foundation,further,researches,into,Males,are,infected,higher,rate,than,females,result,some,data,suggest,that,this,viral,infection,affect,probable,causes,abnormalities,expression,angiotensin,converting,enzyme,testes,indirectly,induces,immune,response,damages,cells,receptor,binding,activity,fever,may,testicular,testosterone,level,decreased,more,susceptible,due,differences,physiology,seeks,offer,insights,potential,well
AB值:
0.535106
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