典型文献
Severe progression of autoimmune hepatitis in a young COVID?19 adult patient: A case report
文献摘要：
Rationale: The impact of COVID-19 in patients with autoimmune liver disease treated with immunosuppressive therapy has not been described so far. This case report describes the clinical course of a patient with autoimmune hepatitis (AIH) who developed COVID-19 and the features of cytokine syndrome leading to its deterioration in our intensive care unit. Patient's Concern: A 28-year-old male presented with generalized anasarca for two weeks and chronic liver disease for 8 months. Diagnosis: AIH and Covid-19 with features of cytokine storm syndrome. Interventions: Intravenous furosemide, mannitol, syrup lactulose, steroids (prednisolone 40 mg), azathioprine 1 mg/kg body weight, rifaximin, vitamin K, and blood products. Outcomes: The patient had hepatic encephalopathy and AIH and died on the 10th day after admission despite ventilatory support, sustained low-efficiency hemodialysis, and resuscition. Lessons: The dramatic release of cytokines and the inflammatory-immune responses not only alter the pathophysiology but also affects the onset and severity of disease progression in patients with AIH.
文献关键词：
中图分类号：
作者姓名：
Neeraj Kumar;Sushant Satyapriya;Shaik Mohammad Tahaseen;Kunal Singh;Abhyuday Kumar
作者机构：
Department of Trauma&Emergency,AIIMS Patna,Bihar,India,801505;Department of Anaesthesiology,AIIMS Patna,Bihar,India,801505;Department of Medicine,AIIMS Patna,Bihar,India,801505
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引用格式：
[1]Neeraj Kumar;Sushant Satyapriya;Shaik Mohammad Tahaseen;Kunal Singh;Abhyuday Kumar-.Severe progression of autoimmune hepatitis in a young COVID?19 adult patient: A case report)[J].急性病杂志（英文版）,2022(04):161-164
A类：
anasarca,syrup,rifaximin,resuscition
B类：
Severe,progression,autoimmune,hepatitis,young,adult,case,report,Rationale,impact,patients,liver,disease,treated,immunosuppressive,therapy,has,not,been,described,far,This,describes,clinical,course,AIH,who,developed,features,syndrome,leading,its,deterioration,intensive,care,unit,Patient,Concern,year,old,male,presented,generalized,two,weeks,chronic,months,Diagnosis,Covid,storm,Interventions,Intravenous,furosemide,mannitol,lactulose,steroids,prednisolone,azathioprine,body,weight,vitamin,blood,products,Outcomes,had,hepatic,encephalopathy,died,10th,day,after,admission,despite,ventilatory,support,sustained,low,efficiency,hemodialysis,Lessons,dramatic,release,cytokines,inflammatory,responses,only,alter,pathophysiology,but,also,affects,onset,severity
AB值：
0.663741
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