典型文献
Fetal Growth Restriction: Mechanisms, Epidemiology, and Management
文献摘要：
Fetal growth restriction (FGR) is the condition in which a fetus does not reach its intrinsic growth potential and in which the shortterm and long-term risks of severe complications are increased. FGR is a frequent complication of pregnancy with a complex etiology and limited management options, other than timely delivery. The most common pathophysiological mechanism is placental insufficiency, due to many underlying causes such as maternal vascular malperfusion, fetal vascular malperfusion and villitis.Identifying truly growth restricted fetuses remains challenging. To date, FGR is often defined by a cut-off of the estimated fetal weight below a certain percentile on a population-based standard. However, small fetal size as a single marker does not discriminate adequately between fetuses or newborns that are constitutionally small but healthy and fetuses or newborns that are growth restricted and thus at risk for adverse outcomes. In 2016, the consensus definition of FGR was internationally accepted to better pinpoint the FGR population.In this review we will discuss the contemporary diagnosis and management issues. Different diagnostic markers are considered, like Doppler measurements, estimated fetal growth, interval growth, fetal movements, biomarkers, and placental markers.
文献关键词：
Fetal growth restriction;Growth restriction in the newborn;Placental insufficiency syndrome;Doppler measurements;Biomarkers;Placental function
中图分类号：
作者姓名：
Kamphof Hester D.;Posthuma Selina;Gordijn Sanne J.;Ganzevoort Wessel
作者机构：
Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands;Department of Obstetrics & Gynecology, Amsterdam UMC, University of Amsterdam, 1100 DD Amsterdam, The Netherlands;Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, University of Amsterdam, 1100 DD Amsterdam, The Netherlands
文献出处：
引用格式：
[1]Kamphof Hester D.;Posthuma Selina;Gordijn Sanne J.;Ganzevoort Wessel-.Fetal Growth Restriction: Mechanisms, Epidemiology, and Management)[J].母胎医学杂志（英文）,2022(03):186-196
A类：
shortterm,constitutionally
B类：
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AB值：
0.592272
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