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典型文献
Drug research and development opportunities in low-and middle-income countries: accelerating traditional medicine through systematic utilization and comprehensive synergy
文献摘要:
Background::Though the utilization of traditional medicine has been proposed for modern drug research and development (R&D), limited research has discussed its feasible paths. In this commentary, we summarized key factors for new drug R&D under limited resources by reviewing China’s discovery of artemisinin, and raised suggestions to utilize traditional medicines in low-and middle-income countries (LMICs).Main text::We suggested that systematic utilization of traditional medicine, outstanding synergy of research units at all levels and timely information-sharing mechanism should be achieved to establish a comprehensive and efficient R&D system, especially under low-resource settings. In the case of artemisinin discovery, Chinese scientists integrated documented traditional medicine experiences and modern approaches to develop drug candidates timely. Due to limited R&D resources, China adopted a collaborative way, motivating nearly all domestic research units at different levels, to develop antimalarial products. Moreover, the excellent synergy among all units through efficient information-sharing mechanisms greatly avoided work repetition and accelerated the R&D process.Conclusion::Traditional medicines inspires drug discoveries in LMICs, while a comprehensive and efficient R&D system could accelerate its R&D process and save investment. The discovery of artemisinin in China gave a reliable pattern to promote sustainable development of traditional medicines and a good example to realize R&D of traditional medicine under low-resource settings.
文献关键词:
Traditional medicine;Research and development;Low-and middle-income countries
作者姓名:
Liu Guangqi;Xie Yan;Sun Yinuo;Zhang Kaixuan;Ma Jiyan;Huang Yangmu
作者机构:
Department of Global Health, Peking University School of Public Health, 38 Xue Yuan Road, Haidian District, Beijing 100191, China;Institute for Global Health, Peking University, Beijing, China
引用格式:
[1]Liu Guangqi;Xie Yan;Sun Yinuo;Zhang Kaixuan;Ma Jiyan;Huang Yangmu-.Drug research and development opportunities in low-and middle-income countries: accelerating traditional medicine through systematic utilization and comprehensive synergy)[J].贫困所致传染病(英文),2022(02):77-80
A类:
B类:
Drug,research,development,opportunities,low,middle,income,countries,accelerating,traditional,through,systematic,utilization,comprehensive,synergy,Background,Though,has,been,proposed,modern,drug,limited,discussed,feasible,paths,In,this,commentary,we,summarized,key,factors,new,under,resources,by,reviewing,China,discovery,artemisinin,raised,suggestions,utilize,medicines,LMICs,Main,text,We,suggested,that,outstanding,units,levels,timely,information,sharing,should,achieved,establish,efficient,especially,settings,case,Chinese,scientists,integrated,documented,experiences,approaches,candidates,Due,adopted,collaborative,way,motivating,nearly,domestic,different,antimalarial,products,Moreover,excellent,among,mechanisms,greatly,avoided,work,repetition,accelerated,process,Conclusion,Traditional,inspires,discoveries,while,could,save,investment,gave,reliable,pattern,promote,sustainable,good,example,realize,Research,Low
AB值:
0.543065
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