典型文献
Antibacterial activities of a novel Cu-bearing high-entropy alloy against multi-drug-resistant Acinetobacter baumannii and Staphylococcus aureus
文献摘要:
Acinetobacter baumannii and methicillin-resis-tant Staphylococcus aureus (MRSA) are two prevalent pathogens and have developed high resistant to most antibiotics.Therefore,it is a pressing need to develop a new method to inhibit the spread of drug-resistant bacteria.Copper containing high-entropy alloy (HEA,Alo.4CoCr-CuFeNi) is a new kind of alloy material,which shows extensive antibacterial activity and mechanical properties in our previous research.This study further develops another HEA (CoCrCuFeNi) and evaluates its resistance against gram-negative A.baumannii and Gram-positive MRSA.The antibacterial tests show that the antibacterial rate of the HEA toward both bacteria reached nearly 99%,far better than the traditional copper-bearing 304 stainless steel (304 Cu-SS).The biofilm observation shows that the HEA could not only kill the planktonic bacteria,but also effectively inhibit the formation of biofilm.These data demonstrate that CoCrCuFeNi HEA possesses effective antibacterial and antibiofilm activities,making it a poten-tial candidate for using in hospital,food industry,and domestic kitchens.
文献关键词:
中图分类号:
作者姓名:
En-Ze Zhou;Guang-Yu Ren;Yun-Ling Sun;Yong-Qiang Fan;Yi Yang;Ming-Yue Sun;Da-Ke Xu;Yi-Ping Lu;Jian-Jun Wang;Hua-Bing Li;Fu-Hui Wang
作者机构:
Shenyang National Laboratory for Materials Science,Key Laboratory for Anisotrotropy and Texture of Materials (Ministry of Education),School of Materials Science and Engineering,Northeastern University,Shenyang 110819,China;Key Laboratory of Solidification Control and Digital Preparation Technology (Liaoning Province),School of Materials Science and Engineering,Dalian University of Technology,Dalian 116024,China;General Hospital of Northern Theater Command,Shenyang 110819,China;School of Metallurgy,Northeastern University,Shenyang 110819,China
文献出处:
引用格式:
[1]En-Ze Zhou;Guang-Yu Ren;Yun-Ling Sun;Yong-Qiang Fan;Yi Yang;Ming-Yue Sun;Da-Ke Xu;Yi-Ping Lu;Jian-Jun Wang;Hua-Bing Li;Fu-Hui Wang-.Antibacterial activities of a novel Cu-bearing high-entropy alloy against multi-drug-resistant Acinetobacter baumannii and Staphylococcus aureus)[J].稀有金属(英文版),2022(02):570-579
A类:
4CoCr,CuFeNi
B类:
Antibacterial,activities,novel,bearing,high,entropy,alloy,against,multi,drug,resistant,Acinetobacter,baumannii,Staphylococcus,aureus,methicillin,MRSA,are,two,prevalent,pathogens,have,developed,most,antibiotics,Therefore,pressing,need,new,method,inhibit,spread,Copper,containing,HEA,Alo,kind,material,which,shows,extensive,antibacterial,activity,mechanical,properties,our,previous,research,This,study,further,develops,another,CoCrCuFeNi,evaluates,its,resistance,gram,negative,Gram,positive,tests,that,toward,both,reached,nearly,far,better,than,traditional,copper,stainless,steel,SS,observation,could,only,kill,planktonic,but,also,effectively,formation,These,data,demonstrate,possesses,antibiofilm,making,poten,tial,candidate,using,hospital,food,industry,domestic,kitchens
AB值:
0.606731
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