典型文献
A smart nanoprobe based on luminescent terbium metal-organic framework coated gold nanorods for monitoring and photo-stimulated combined thermal-chemotherapy
文献摘要:
Real-time monitoring and accurate treatment are of great significance for reducing the side effects during the cancer therapy. In this work, we rationally prepared a smart nanoprobe based on core-shell terbium metal-organic gramework (MOF) with highly effective photothermal conversion capacity and drug release efficiency under near-infrared light irradiation for real-time fluorescence imaging-guided multimodal therapy. The nanoprobe can achieve prominent photothermal therapy and controllable drug release, act as a fluorescence thermometer, and also real-time feedback of temperature is expected to be achieved. At the same time, the two-photon ligand design significantly improves the tissue penetration ability of the nanoprobe. Our work is expected to provide a reference for precise treatment and real-time monitoring of tumors and at the same time provide new ideas for the formulation of individualized treatment plans.
文献关键词:
中图分类号:
作者姓名:
Tong Zhang;Liying Qin;Liangliang Liu;Meina Zhang;Tianyi Du;Yifan Fan;Huicheng Yan;Pingru Su;Ping Zhou;Yu Tang
作者机构:
Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province,College of Chemistry and Chemical Engineering,Lanzhou University,Lanzhou 730000,China;School/Hospital of Stomatology,Lanzhou University,Lanzhou 730000,China
文献出处:
引用格式:
[1]Tong Zhang;Liying Qin;Liangliang Liu;Meina Zhang;Tianyi Du;Yifan Fan;Huicheng Yan;Pingru Su;Ping Zhou;Yu Tang-.A smart nanoprobe based on luminescent terbium metal-organic framework coated gold nanorods for monitoring and photo-stimulated combined thermal-chemotherapy)[J].稀土学报(英文版),2022(09):1371-1381
A类:
gramework
B类:
smart,nanoprobe,luminescent,terbium,metal,organic,framework,coated,gold,nanorods,monitoring,stimulated,combined,chemotherapy,Real,accurate,treatment,great,significance,reducing,side,effects,during,cancer,In,this,we,rationally,prepared,core,shell,MOF,highly,effective,photothermal,conversion,capacity,drug,release,efficiency,under,near,infrared,light,irradiation,real,fluorescence,imaging,guided,multimodal,prominent,controllable,act,thermometer,also,feedback,temperature,expected,achieved,At,same,two,photon,ligand,design,significantly,improves,tissue,penetration,ability,Our,provide,reference,precise,tumors,new,ideas,formulation,individualized,plans
AB值:
0.593962
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