典型文献
A rare case of giant panda cancer: Pancreatic ductal adenocarcinoma
文献摘要:
Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant cancer of the diges-tive system common among humans. However, it is rarely reported in wild animals. In 2018, a giant panda died in the Beijing Zoo. During subsequent histological observa-tion of the pancreas, it was discovered that the glandular epithelial cells had lost the pancreatic acinar structure, tubular areas with obvious structure in the pancreas, and the ductal epithelium was substituted by high columnar mucus cells. Masson stain-ing showed that there were several fibrous tissue proliferative reactions around the ductal adenocarcinoma and immunohistochemical staining revealed that CK7 and CK19 were positively expressed in the pancreatic tissue. Therefore, the pathological diagnosis indicated that the panda had PDAC. In this paper, the panda ' s living condi-tions and pathological diagnosis results are examined, with the aim of providing a reference point for the future diagnosis of wild animal tumors.
文献关键词:
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作者姓名:
Yunsheng Wang;Maohua Xia;Xiangxiang Li;Xinxin Guo;Yan Lu;Sufen Zhao;Tianchun Pu
作者机构:
Wildlife Pathological diagnosis Laboratory, Department of Veterinary Hospital , Beijing Zoo , Beijing , China;Beijing Key Laboratory of Captive Wildlife Technologies , Beijing Zoo , Beijing , China;Wildlife Clinical Laboratory, Department of Veterinary Hospital , Beijing Zoo ,Beijing , China
文献出处:
引用格式:
[1]Yunsheng Wang;Maohua Xia;Xiangxiang Li;Xinxin Guo;Yan Lu;Sufen Zhao;Tianchun Pu-.A rare case of giant panda cancer: Pancreatic ductal adenocarcinoma)[J].动物模型与实验医学(英文),2022(06):582-586
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case,giant,panda,cancer,Pancreatic,ductal,adenocarcinoma,PDAC,highly,malignant,diges,system,common,among,humans,However,rarely,reported,wild,animals,In,died,Beijing,Zoo,During,subsequent,histological,observa,pancreas,was,discovered,that,glandular,epithelial,cells,had,lost,pancreatic,acinar,structure,tubular,areas,obvious,epithelium,substituted,by,columnar,mucus,Masson,showed,there,were,several,fibrous,tissue,proliferative,reactions,around,immunohistochemical,staining,revealed,CK7,CK19,positively,expressed,Therefore,pathological,diagnosis,indicated,this,paper,living,condi,results,examined,aim,providing,reference,point,future,tumors
AB值:
0.608903
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