典型文献
Research progress and prospects of circulating tumor cells in hepatocellular carcinoma
文献摘要:
Hepatocellular carcinoma(HCC)is one of the most common cancers and is the second leading cause of cancer-related deaths worldwide[1,2].The main therapies for HCC include surgical re-section,local ablation,or liver transplantation,which are only applied to early-stage HCC.However,most patients at the time of initial HCC diagnosis have already progressed to an advanced stage,and survival can only be prolonged finitely via palliative therapies,such as transarterial chemoembolization,systemic ther-apy with tyrosine kinase inhibitors,and selective internal radiation therapy[3,4].Moreover,as HCC has a high recurrence rate,the treatment efficacy is not satisfactory[5].Currently,the diagnosis and monitoring of HCC primarily depend on serum biomarker de-tection,pathological examination,and imaging analysis.Common serum markers display poor diagnostic performance,and imaging and pathological examinations have limitations in diagnostic accu-racy and sensitivity[6,7].Therefore,we urgently require better ap-proaches for the diagnosis and monitoring of HCC.
文献关键词:
中图分类号:
作者姓名:
Chang-Can Li;Hua-Yu Yang;Yi-Lei Mao
作者机构:
Department of Liver Surgery,Peking Union Medical College(PUMC)Hospital,PUMC&Chinese Academy of Medical Sciences(CAMS),Beijing 100730,China
文献出处:
引用格式:
[1]Chang-Can Li;Hua-Yu Yang;Yi-Lei Mao-.Research progress and prospects of circulating tumor cells in hepatocellular carcinoma)[J].国际肝胆胰疾病杂志(英文版),2022(06):514-515
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B类:
Research,prospects,circulating,tumor,cells,hepatocellular,carcinoma,Hepatocellular,HCC,one,most,common,cancers,second,leading,cause,related,deaths,worldwide,main,therapies,include,surgical,section,local,ablation,liver,transplantation,which,are,only,applied,early,stage,However,patients,initial,diagnosis,have,already,progressed,advanced,survival,prolonged,finitely,via,palliative,such,transarterial,chemoembolization,systemic,tyrosine,kinase,inhibitors,selective,internal,radiation,therapy,Moreover,has,high,recurrence,rate,treatment,efficacy,not,satisfactory,Currently,monitoring,primarily,depend,serum,biomarker,tection,pathological,imaging,analysis,Common,markers,display,poor,diagnostic,performance,examinations,limitations,accu,racy,sensitivity,Therefore,urgently,require,better,proaches
AB值:
0.663001
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