典型文献
Effects of Environmental Cadmium on Cadmium Accumulation, Oxidative Response, and Microelements Regulation in the Liver and Kidney of Hexagrammos otakii
文献摘要:
The effects of cadmium (Cd) on metal accumulation, microelements contents, and antioxidant responses in Hexagram- mos otakii were studied. The fish were exposed to 0.2, 2.5, or 10 μg L?1 Cd for 12 or 24 days. Then, the concentration of Cd and mi- croelements (Ca, Fe, Zn, and Se) were determined in the liver and kidney. Moreover, the activities of antioxidant enzymes including superoxide dismutase (SOD), catalase (CAT), and glutathione-S-transferase (GST), and the content of malondialdehyde (MDA) in the liver and kidney were also measured. A continuous accumulation of Cd was observed throughout the experimental period. Cd accumulation was higher in liver than that in the kidney, while Ca and Fe contents were lower in liver than those in the kidney. Cd exposure resulted in a decrease of Ca and Fe concentrations in the kidney, while there was no effect on the liver. Zn and Se remained unaffected with exposure to Cd. Cd exposure induced severe oxidative stress in H. otakii, as indicated by significant induction of the activities of SOD, CAT, and GST, and a simultaneous increase of MDA content. These data show that antioxidant enzymes and mi-croelements contents can be used as potential biomarkers to monitor environmental health in fish.
文献关键词:
中图分类号:
作者姓名:
HU Fawen;SUN Ming;LI Li;GAO Fengxiang;JIAN Yuxia;WANG Xue;WANG Xiaolong;GUO Wen
作者机构:
Marine Biology Institute of Shandong Province,Healthy Mariculture Engineering Research Center of Shandong Province,Qingdao 266104,China
文献出处:
引用格式:
[1]HU Fawen;SUN Ming;LI Li;GAO Fengxiang;JIAN Yuxia;WANG Xue;WANG Xiaolong;GUO Wen-.Effects of Environmental Cadmium on Cadmium Accumulation, Oxidative Response, and Microelements Regulation in the Liver and Kidney of Hexagrammos otakii)[J].中国海洋大学学报(自然科学英文版),2022(02):479-485
A类:
Microelements,microelements,Hexagram,croelements
B类:
Effects,Environmental,Cadmium,Accumulation,Oxidative,Response,Regulation,Liver,Kidney,Hexagrammos,otakii,effects,cadmium,Cd,metal,accumulation,contents,antioxidant,responses,were,studied,fish,exposed,days,Then,Se,determined,liver,kidney,Moreover,activities,enzymes,including,superoxide,dismutase,catalase,CAT,glutathione,transferase,GST,malondialdehyde,also,measured,continuous,was,observed,throughout,experimental,period,higher,than,that,while,lower,those,exposure,resulted,decrease,concentrations,there,no,remained,unaffected,induced,severe,oxidative,stress,indicated,by,significant,induction,simultaneous,increase,These,data,show,be,used,potential,biomarkers,monitor,environmental,health
AB值:
0.468609
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