典型文献
OsDMI3-mediated OsUXS3 phosphorylation improves oxidative stress tolerance by modulating OsCATB protein abundance in rice
文献摘要：
Calcium (Ca2+)/calmodulin (CaM)-dependent pro-tein kinase (CCaMK) is an important positive reg-ulator of antioxidant defenses and tolerance against oxidative stress. However, the underlying molecular mechanisms are largely unknown. Here, we report that the rice (Oryza sativa) CCaMK (OsDMI3) physically interacts with and phosphor-ylates OsUXS3, a cytosol-localized UDP-xylose synthase. Genetic and biochemical evidence demonstrated that OsUXS3 acts downstream of OsDMI3 to enhance the oxidative stress tolerance conferred by higher catalase (CAT) activity. In-deed, OsUXS3 interacted with CAT isozyme B (OsCATB), and this interaction was required to increase OsCATB protein abundance under oxi-dative stress conditions. Furthermore, we showed that OsDMI3 phosphorylates OsUXS3 on residue Ser-245, thereby further promoting the interaction between OsUXS3 and OsCATB. Our results in-dicate that OsDMI3 promotes the association of OsUXS3 with OsCATB to enhance CAT activity under oxidative stress. These findings reveal OsUXS3 as a direct target of OsDMI3 and dem-onstrate its involvement in antioxidant defense.
文献关键词：
中图分类号：
作者姓名：
Lan Ni;Qingwen Wang;Chao Chen;Shuang Wang;Tao Shen;Jingjing Jiang;Zhenzhen Cui;Kaiyue Li;Qiqing Yang;Mingyi Jiang
作者机构：
College of Life Sciences,National Key Laboratory of Crop Genetics and Germplasm Enhancement,Key Laboratory of Crop Physiology Ecology and Production Management,Ministry of Agriculture,Nanjing Agricultural University,Nanjing 210095,China;Southern Regional Collaborative Innovation Center for Grain and Oil Crops in China,Hunan Agricultural University,Changsha 410128,China
文献出处：
引用格式：
[1]Lan Ni;Qingwen Wang;Chao Chen;Shuang Wang;Tao Shen;Jingjing Jiang;Zhenzhen Cui;Kaiyue Li;Qiqing Yang;Mingyi Jiang-.OsDMI3-mediated OsUXS3 phosphorylation improves oxidative stress tolerance by modulating OsCATB protein abundance in rice)[J].植物学报（英文版）,2022(05):1087-1101
A类：
OsDMI3,OsUXS3,OsCATB,CCaMK,ylates,deed
B类：
mediated,phosphorylation,improves,oxidative,stress,tolerance,modulating,protein,abundance,rice,Calcium,Ca2+,calmodulin,dependent,kinase,important,positive,reg,ulator,antioxidant,defenses,against,However,underlying,molecular,mechanisms,are,largely,unknown,Here,report,that,Oryza,sativa,physically,interacts,cytosol,localized,UDP,xylose,synthase,Genetic,biochemical,evidence,demonstrated,downstream,enhance,conferred,higher,catalase,activity,In,interacted,isozyme,this,interaction,was,required,increase,conditions,Furthermore,showed,phosphorylates,residue,Ser,thereby,further,promoting,between,Our,results,dicate,promotes,association,These,findings,reveal,direct,target,its,involvement
AB值：
0.459972
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