典型文献
Radiolabeled peptide probe for tumor imaging
文献摘要：
Radionuclide imaging is now the premier imaging method in clinical practice for its high sensitivity and tomographic capability.Current clinically available radio imaging methods mostly use positron-emission tomography(PET)and single-photon emission computed tomography(SPECT)to detect anatomic abnor-malities that conventional imaging techniques typically have challenges for visualizing.Contrast agents are indispensable for radionuclide imaging,and the radionuclide is always attached to a suitable vector that achieves targeted delivery.Nowadays,peptides have attracted increasing interest in targeting vec-tors of contrast agents,mainly due to their high specificity for target receptors at nanomolar concentra-tions and low toxicity.Radiolabeled peptide probes as kinds of PET/SPECT tracers had become essential tools for clinical radionuclide diagnosis.This review mainly summarizes radiolabeled peptide probes for bioimaging,including fundamental concepts of radiolabeled peptide probe design,some typical peptide analogs radiocontrast agents for PET.SPECT.and the combination imaging.
文献关键词：
中图分类号：
作者姓名：
Ya-Qiong Yan;Hao Wang;Yuliang Zhao
作者机构：
CAS Center for Excellence in Nanoscience,CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety,National Center for Nanoscience and Technology(NCNST),Beijing 100190,China
文献出处：
引用格式：
[1]Ya-Qiong Yan;Hao Wang;Yuliang Zhao-.Radiolabeled peptide probe for tumor imaging)[J].中国化学快报（英文版）,2022(07):3361-3370
A类：
Radiolabeled,Radionuclide,abnor,malities,radiocontrast
B类：
tumor,now,premier,practice,its,high,sensitivity,tomographic,capability,Current,clinically,available,methods,mostly,use,positron,emission,tomography,PET,single,photon,computed,SPECT,detect,anatomic,that,conventional,techniques,typically,have,challenges,visualizing,Contrast,agents,are,indispensable,radionuclide,always,attached,suitable,vector,achieves,targeted,delivery,Nowadays,peptides,attracted,increasing,interest,targeting,mainly,due,their,specificity,receptors,nanomolar,concentra,tions,low,toxicity,probes,kinds,tracers,had,become,essential,tools,diagnosis,This,review,summarizes,radiolabeled,bioimaging,including,fundamental,concepts,design,some,analogs,combination
AB值：
0.566282
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