典型文献
Forthrightly monitoring ferroptosis induced by endoplasmic reticulum stresses through fluorescence lifetime imaging of microviscosity increases with a specific rotor
文献摘要:
To test the hypothesis that the microviscosity changes of Endoplasmic Reticulum(ER)can be a useful indicator of ferroptosis promoted by ER Stresses(ERS),a new ER targeting viscosity rotor,L-Vis-1 was developed and applied in the quantitation of viscosity by FLIM imaging in live cells.The FLIM imag-ing exhibited an excellent resolution almost as good as the corresponding confocal imaging,more sig-nificantly,during ferroptosis processes promoted by different types of ERS,the viscosity increases were clearly monitored by FLIM of L-Vis-1 within ER,which has not been demonstrated before.
文献关键词:
中图分类号:
作者姓名:
Chuanhao Liu;Lin Zhou;Lijuan Xie;Ying Zheng;Huizi Man;Yi Xiao
作者机构:
Engineering Research Center of Molecular Medicine of Ministry of Education,Key Laboratory of Fujian Molecular Medicine,School of Medicine,Huaqiao University,Quanzhou 362021,China;State Key Laboratory of Fine Chemicals,Dalian University of Technology,Dalian 116024,China
文献出处:
引用格式:
[1]Chuanhao Liu;Lin Zhou;Lijuan Xie;Ying Zheng;Huizi Man;Yi Xiao-.Forthrightly monitoring ferroptosis induced by endoplasmic reticulum stresses through fluorescence lifetime imaging of microviscosity increases with a specific rotor)[J].中国化学快报(英文版),2022(05):2537-2540
A类:
Forthrightly,microviscosity,FLIM
B类:
monitoring,ferroptosis,induced,by,endoplasmic,reticulum,stresses,through,fluorescence,lifetime,imaging,increases,specific,rotor,To,test,hypothesis,that,changes,Endoplasmic,Reticulum,useful,indicator,promoted,Stresses,ERS,new,targeting,Vis,was,developed,applied,quantitation,live,cells,exhibited,excellent,resolution,almost,good,corresponding,confocal,more,sig,nificantly,during,processes,different,types,were,clearly,monitored,within,which,has,not,been,demonstrated,before
AB值:
0.571611
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