首站-论文投稿智能助手
典型文献
Forthrightly monitoring ferroptosis induced by endoplasmic reticulum stresses through fluorescence lifetime imaging of microviscosity increases with a specific rotor
文献摘要:
To test the hypothesis that the microviscosity changes of Endoplasmic Reticulum(ER)can be a useful indicator of ferroptosis promoted by ER Stresses(ERS),a new ER targeting viscosity rotor,L-Vis-1 was developed and applied in the quantitation of viscosity by FLIM imaging in live cells.The FLIM imag-ing exhibited an excellent resolution almost as good as the corresponding confocal imaging,more sig-nificantly,during ferroptosis processes promoted by different types of ERS,the viscosity increases were clearly monitored by FLIM of L-Vis-1 within ER,which has not been demonstrated before.
文献关键词:
作者姓名:
Chuanhao Liu;Lin Zhou;Lijuan Xie;Ying Zheng;Huizi Man;Yi Xiao
作者机构:
Engineering Research Center of Molecular Medicine of Ministry of Education,Key Laboratory of Fujian Molecular Medicine,School of Medicine,Huaqiao University,Quanzhou 362021,China;State Key Laboratory of Fine Chemicals,Dalian University of Technology,Dalian 116024,China
引用格式:
[1]Chuanhao Liu;Lin Zhou;Lijuan Xie;Ying Zheng;Huizi Man;Yi Xiao-.Forthrightly monitoring ferroptosis induced by endoplasmic reticulum stresses through fluorescence lifetime imaging of microviscosity increases with a specific rotor)[J].中国化学快报(英文版),2022(05):2537-2540
A类:
Forthrightly,microviscosity,FLIM
B类:
monitoring,ferroptosis,induced,by,endoplasmic,reticulum,stresses,through,fluorescence,lifetime,imaging,increases,specific,rotor,To,test,hypothesis,that,changes,Endoplasmic,Reticulum,useful,indicator,promoted,Stresses,ERS,new,targeting,Vis,was,developed,applied,quantitation,live,cells,exhibited,excellent,resolution,almost,good,corresponding,confocal,more,sig,nificantly,during,processes,different,types,were,clearly,monitored,within,which,has,not,been,demonstrated,before
AB值:
0.571611
相似文献
Abrogation of HnRNP L enhances anti-PD-1 therapy efficacy via diminishing PD-L1 and promoting CD8+T cell-mediated ferroptosis in castration-resistant prostate cancer
Xumin Zhou;Libin Zou;Hangyu Liao;Junqi Luo;Taowei Yang;Jun Wu;Wenbin Chen;Kaihui Wu;Shengren Cen;Daojun Lv;Fangpeng Shu;Yu Yang;Chun Li;Bingkun Li;Xiangming Mao-Department of Urology,Zhujiang Hospital,Southern Medical University,Guangzhou 510280,China;Second Department of Hepatobiliary Surgery,Zhujiang Hospital,Southern Medical University,Guangzhou 510280,China;Department of Urology,Minimally Invasive Surgery Center,the First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510120,China;Department of Urology,Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou 510623,China;Department of Urology,Peking University Shenzhen Hospital,Shenzhen 518036,China;Nursing Department,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China
A mitochondria-targeted AIE photosensitizer for enhancing specificity and efficacy of ferroptosis inducer
Shan Wang;Chao Chen;Jianmin Wu;Jianyu Zhang;Jacky W.Y.Lam;Hongyang Wang;Lei Chen;Ben Zhong Tang-Fudan University Shanghai Cancer Center Shanghai Medical College,Fudan University,Shanghai 200032,China;Department of Chemistry,Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction,Institute for Advanced Study,State Key Laboratory of Molecular Nanoscience,Division of Life Science,and Department of Chemical and Biological Engineering,The Hong Kong University of Science and Technology,Hong Kong 999077,China;Institute of Metabolism and Integrative Biology,Fudan University,Shanghai 200433,China;The International Cooperation Laboratory on Signal Transduction,Eastern Hepatobiliary Surgery Hospital,Second Military Medical University,Shanghai 200438,China;National Center for Liver Cancer Shanghai 200441,China;Shenzhen Institute of Aggregate Science and Technology,School of Science and Engineering,The Chinese University of Hong Kong,Shenzhen 518172,China;AIE Institute,Guangzhou Development District,Guangzhou 510530,China
机标中图分类号,由域田数据科技根据网络公开资料自动分析生成,仅供学习研究参考。