典型文献
Rosiglitazone disrupts pancreatic ductal adenocarcinoma progression by activating the tumor suppressor ESE3/EHF
文献摘要：
Pancreatic ductal adenocarcinoma (PDAC), the most com-mon histologic type of pancreatic cancer, is among the most lethal cancers, and is associated with poor prognosis because of its inherent chemoresistant nature and metastatic capacity1. Extensive evidence has shown that cancer stem cells (CSCs), a subpopulation of highly plastic "stem"-like cells within the PDAC, mediate this chemoresistantce and metastatic capacity2. CSCs have unique metabolic, invasive, and chemoresistance properties that enable them to continually self-renew and escape standard chemotherapeutic elimination in PDAC, thus often rendering treatments ineffective3,4.
文献关键词：
中图分类号：
作者姓名：
Hongquan Wang;Shuang Wu;Yan Wang;Bo Tang
作者机构：
Department of Pancreatic Cancer,Tianjin Medical University Cancer Institute&Hospital,National Clinical Research Center for Cancer,Key Laboratory of Cancer Prevention and Therapy,Tianjin,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China
文献出处：
引用格式：
[1]Hongquan Wang;Shuang Wu;Yan Wang;Bo Tang-.Rosiglitazone disrupts pancreatic ductal adenocarcinoma progression by activating the tumor suppressor ESE3/EHF)[J].癌症生物学与医学（英文版）,2022(07):945-947
A类：
ESE3,chemoresistant,capacity1,chemoresistantce,capacity2,ineffective3
B类：
Rosiglitazone,disrupts,pancreatic,ductal,adenocarcinoma,progression,by,activating,tumor,suppressor,EHF,Pancreatic,PDAC,most,com,histologic,type,among,lethal,cancers,associated,poor,prognosis,because,its,inherent,nature,metastatic,Extensive,evidence,has,shown,that,stem,cells,CSCs,subpopulation,highly,plastic,like,within,mediate,this,have,unique,metabolic,invasive,chemoresistance,properties,enable,them,continually,self,renew,escape,standard,chemotherapeutic,elimination,thus,often,rendering,treatments
AB值：
0.65656
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
